Examples of Chimeras Dan Lipsker, MD, PhD; Elisabeth Flory, MD; Marie-Louise Wiesel, MD; et al Background Chimerism, especially in the absence of sexual ambiguity, is extremely rare in humans. We report the case of a 6-year-old boy whose skin pigmentary abnormalities revealed chimerism. Observations The boy had no remarkable previous […]
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A case of doping or a ‘vanishing twin’?
By GINA KOLATAMAY 12, 2005 Last month, when the champion American cyclist Tyler Hamilton was accused of blood doping, or transfusing himself with another person’s blood to increase his oxygen-carrying red cells, he offered a surprising defense: The small amount of different blood found mixed in with his own must have come from […]
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Beautiful sonogram shows dying twin holding unborn sister’s hand
HUTCHINSON, Kan. — Ian and Brittani McIntire didn’t plan on having any more kids — much less, twins. “We went in for our 6 week sonogram and they just said there’s one heartbeat and here’s another,” Brittani said. From shock, to excitement, to hearing news no parent expects. With a hole in his heart and […]
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Dying twin holds sister’s hand in utero
A family will hold on to a sonogram picture taken Tuesday that warmed everyone’s heart. It appeared to show their unborn twins holding hands. (Source: KWCH/CNN) A family will hold on to a sonogram picture taken Tuesday that warmed everyone’s heart. It appeared to show their unborn twins holding hands. (Source: KWCH/CNN) HUTCHINSON, KS (KWCH/CNN) […]
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Adventures in the Science of the Superorganism
By David Wallace-Wells It is not only possible, it has in fact happened that a woman who vaginally conceived a child, then vaginally delivered her, had Protective Services threaten to take the child when a maternity test showed she was not, in fact, the mother. Nor was she the mother of her second child, genetically. Or […]
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This Man Failed A Paternity Test Due To His Vanished Twin’s DNA
By Dan Vergano A 34-year-old U.S. man is the first-ever reported case of a paternity test fooled by a human “chimera” — someone with extra genes absorbed from a nascent twin lost in early pregnancy. About 1 in 8 single childbirths are thought to have started as multiple pregnancies. Cells from these miscarried siblings are sometimes absorbed in […]
Continue ReadingA Hypothesis for the Aetiology of Spastic Cerebral Palsy: The Vanishing Twin
Written by Administrator Pharoah, P. D. The aetiology of spastic cerebral palsy (CP), in the majority of cases, is not known but the general consensus is that cerebral impairment occurs prepartum. In monochorionic twin pregnancies, death of one twin late in gestation is recognised as being an important risk factor for the surviving cotwin to […]
Continue ReadingThe “Vanishing Twin”: Ultrasonographic Assessment of Fetal Disappearance in the First Trimester
Landy, M.D., H., Weiner, M.D., S., Corson, M.D., S. Review of the sonographic findings of 1000 pregnancies with viable gestations in the first trimester revealed a minimum incidence of twinning of 3.29%. Of these, 21.9% demonstrated the “vanishing twin” phenomenon, often with associated bleeding, but with a good prognosis for the remaining fetus. Ovulation induction […]
Continue ReadingHuman Chorionic Gonadotropin Rise in the Normal and Vanishing Twins Pregnancies
Kelly, M.D., M. P. Results: A vanishing twin occurred in one third of the twin pregnancies. Forty-six percent of these losses occurred after fetal heart activity had been established. Conclusions: Vanishing twin phenomenon occurred in a large proportion of twin pregnancies in this infertility population. Fetal heart activity was not a reliable predictor of continuing […]
Continue ReadingThe Vanishing Twin: Morphologic and Cytogenetic Evaluation of an Ultrasonographic Phenomenon
Rudnicki, M., Vejerslev, L.O., Junge, Jette Abstract. Twin pregnancy was observed by ultrasonographic examination in the 6th week of gestation. After singleton term delivery a thickening of the membranes opposite to the main placenta showed degenerated chorionic villi embedded between one layer of amnion and chorion; no fetal parts were observed. Villus cells from both […]
Continue ReadingClinical and Morphologic Aspects of the Vanishing Twin Phenomenon
Jauniaux, M.D., E., Elkazen, M.D., N., Leroy, M.D., PhD., F., Wilkin, M.D., PhD., P., Rodesch, M.D., PhD, F., Hustin, M.D., PhD., J. The pathologic findings in placentas from ten multiple gestation complicated by the so-called vanishing twin phenomenon were studied to confirm the ultrasonographic evidence. Five pregnancies resulted from in vitro fertilization and embryo transfer, […]
Continue ReadingFirst-Trimester Bleeding and the Vanishing Twin: A Report of Three Cases
Saidi, M.D., M. H. Ultrasonic examination of early pregnancies can lead to the discovery of vanishing twins. The main reason for such an evaluation is bleeding in the first trimester. A vanishing twin need not adversely affect the development of a coexisting singleton pregnancy. Therapeutic dilation and curettage for threatened or inevitable abortion should be […]
Continue ReadingThe Vanishing Twin: Pathologic Confirmation of an Ultrasonographic Phenomenon
Sulak, M.D., L., Dodson, M.D., M. Although the phenomenon of the “vanishing twin” has been noted repeatedly through the use of ultrasound, no confirmatory histologic evidence has been presented previously. This has raised questions concerning the validity of the vanishing twin syndrome. A triplet intrauterine pregnancy was diagnosed ultrasonographically four weeks after in vitro fertilization, […]
Continue ReadingThe Vanishing Twin: An Explanation for Discordance Between Chorionic Villus Karyotype and Fetal Phenotype
Reddy, M.B., K.S., Petersen, S.E., M.B., Antonarakis, S.E., Blakemore, K.J. The proportion of multiple gestation sustaining a very early loss is as high as 63 and 71 per cent according to two other sonographic series (Levi, 1975: Schneider et al., 1979). Employing the 48 per cent figure, ‘vanishing twins’ might be expected in 1.6-2.6 per […]
Continue ReadingA Normal 46,XX Infant with a 46,/69, Placenta: A Major Contribution to the Placenta is from a Resorbed Twin
Callen, D.F., Fernandez, H., Hull, Y.J., Svigos, J.M., Chambers, H.M., Sutherland, G.R. A predominantly triploid 69,XXY placenta was found associated with a normal 46,XX infant. Therefore, a triploid placenta is apparently capable of supporting normal fetal development. The chromosome and pathological results support the conclusion that the triploid placenta originates from a ‘vanishing twin’ pregnancy. […]
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My Twin Died. I Survived
Saturday 20 July 2013 | The Guardian The closeness of twins, two people as one, and particularly the idea of a psychic connection, has always fascinated people. But what happens to the twin who survives when the other dies? In the US they are known as “twinless twins”, in the UK as lone twins, thanks largely […]
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